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PTGX
NASDAQ Life Sciences

CEO Sells $7.5 Million in Stock After Option Exercise

Arie Shkolnikov · Analysis by Wiseek AI
More coverage: Biotech Stocks · Healthcare
Sentiment info
Negative
Importance info
7
Price
$99.95
Mkt Cap
$6.428B
52W Low
$43.2
52W High
$107.84
52W Position info
131% above low
Off High info
7.3% below high
Rel. Volume info
0.9× avg
Market data snapshot near publication time

PTGX has more than doubled off its 52-week low of $43.2.

Summary

Protagonist Therapeutics' CEO sold $7.5 million in company stock after exercising options, contributing to a recent trend of insider sales despite strong Q1 earnings.


Key Events · Ownership and Investor Activity · PTGX

  • CEO Stock Sale

    CEO Dinesh V. Patel sold 75,000 shares of common stock for $7,509,000 at an average price of $100.12 per share.

  • Option Exercise

    The sale followed the exercise of options for 75,000 shares at a strike price of $21.58, valued at $1,618,500.

  • Insider Selling Trend

    This transaction adds to a pattern of insider sales totaling nearly $20 million over the last 90 days, including recent sales by the CFO and a Director.

  • Post-Earnings Sale

    The sale occurred shortly after the company reported a profitable Q1 2026, marking a significant financial turnaround.


Analysis · PTGX · Life Sciences

Protagonist Therapeutics' CEO, Dinesh V. Patel, sold $7.5 million worth of common stock after exercising options. This transaction follows recent positive Q1 earnings, and contributes to a broader pattern of insider sales observed over the past 90 days. While exercising options and selling is a common practice for executives to realize gains, the magnitude of the sale by the CEO could be interpreted as profit-taking rather than a strong signal of future growth confidence, especially given the recent financial turnaround.

How filings like this one have moved

In the 30 days to Oct 19, 2026, 29.4% of the 1386 measured filings Wiseek scored 7 moved their stock by 5% or more by the next session's close. The median move was -0.50%. These are measured outcomes after filings of this importance, not a forecast for this one.

Measured one observation per ticker per day, after exclusions. Current figures: Filing Impact Tracker · open dataset

At the time of this filing, PTGX was trading at $99.95 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $6.4B. The 52-week trading range was $43.20 to $107.84. This filing was assessed with negative market sentiment and an importance score of 7 out of 10.

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PTGX - Latest Insights

PTGX
Aug 28, 2026, 5:37 PM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $147.21
Real-time Price: $134.32 info
Change: -$12.89 (-9%) info
Market Cap: $8.692B info
PTGX
Jun 18, 2026, 4:30 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $112.86
Real-time Price: $134.32 info
Change: +$21.46 (+19%) info
Market Cap: $8.692B info
PTGX
May 11, 2026, 8:25 PM EDT
Filing Type: 4
Importance Score:
8
Price at Filing: $103.50
Real-time Price: $134.32 info
Change: +$30.82 (+30%) info
Market Cap: $8.692B info
PTGX
May 05, 2026, 4:28 PM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $99.21
Real-time Price: $134.32 info
Change: +$35.11 (+35%) info
Market Cap: $8.692B info
PTGX
May 05, 2026, 4:27 PM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $108.00
Real-time Price: $134.32 info
Change: +$26.32 (+24%) info
Market Cap: $8.692B info