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PTGX
NASDAQ Life Sciences

Director Sells $5.9M in Protagonist Therapeutics Stock Following Option Exercise

Arie Shkolnikov · Analysis by Wiseek AI
More coverage: Biotech Stocks · Healthcare
Sentiment info
Negative
Importance info
8
Price
$103.5
Mkt Cap
$6.656B
52W Low
$42.85
52W High
$107.84
52W Position info
142% above low
Off High info
4.0% below high
Rel. Volume info
0.8× avg
Market data snapshot near publication time

PTGX has more than doubled off its 52-week low of $42.85.

Summary

Director Bryan Giraudo sold nearly $6 million worth of Protagonist Therapeutics common stock after exercising options, continuing a trend of insider sales following recent positive financial news.


Key Events · Ownership and Investor Activity · PTGX

  • Director Sells Shares

    Director Bryan Giraudo sold 59,130 shares of common stock for a total of $5,918,880 through open market transactions on May 7-8, 2026.

  • Option Exercise Precedes Sale

    The sale followed the exercise of 36,000 stock options for $238,560 on May 7, 2026, indicating a 'sell-to-cover' or 'exercise and sell' strategy.

  • Timing Near 52-Week Highs

    These transactions occurred with the stock trading near its 52-week high, shortly after the company reported a profitable Q1 2026 and a significant milestone payment.

  • Part of Broader Insider Selling Trend

    This sale contributes to a net insider distribution of over $13 million in the last 90 days, indicating a pattern of insider selling.


Analysis · PTGX · Life Sciences

This significant insider sale by a director, occurring shortly after the company reported a profitable Q1 and a major milestone payment, and with the stock trading near its 52-week high, suggests a lack of conviction despite recent positive developments. The sale contributes to a broader pattern of insider distribution observed over the last 90 days.

How filings like this one have moved

In the 30 days to Oct 21, 2026, 37.5% of the 993 measured filings Wiseek scored 8 moved their stock by 5% or more by the next session's close. The median move was -0.86%. These are measured outcomes after filings of this importance, not a forecast for this one.

Measured one observation per ticker per day, after exclusions. Current figures: Filing Impact Tracker · open dataset

At the time of this filing, PTGX was trading at $103.50 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $6.7B. The 52-week trading range was $42.85 to $107.84. This filing was assessed with negative market sentiment and an importance score of 8 out of 10.

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PTGX - Latest Insights

PTGX
Aug 28, 2026, 5:37 PM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $147.21
Real-time Price: $140.31 info
Change: -$6.90 (-5%) info
Market Cap: $9.079B info
PTGX
Jun 18, 2026, 4:30 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $112.86
Real-time Price: $140.31 info
Change: +$27.45 (+24%) info
Market Cap: $9.079B info
PTGX
May 12, 2026, 7:28 PM EDT
Filing Type: 4
Importance Score:
7
Price at Filing: $99.95
Real-time Price: $140.31 info
Change: +$40.36 (+40%) info
Market Cap: $9.079B info
PTGX
May 05, 2026, 4:28 PM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $99.21
Real-time Price: $140.31 info
Change: +$41.10 (+41%) info
Market Cap: $9.079B info
PTGX
May 05, 2026, 4:27 PM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $108.00
Real-time Price: $140.31 info
Change: +$32.31 (+30%) info
Market Cap: $9.079B info