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Adagene Inc.

corporate_fare Company Profile

Adagene Inc.

ADAG·NASDAQ·Life Sciences·CIK 0001818838

Adagene Inc. is a clinical-stage biotechnology company focused on researching, developing, and producing monoclonal antibody drugs for cancers in the People's Republic of China. The company's lead product candidate is ADG126, a masked fully-human anti-CTLA-4 mAb, which is in phase 1b/2 clinical development for cancer treatment. Adagene also develops ADG116, a fully human anti-CTLA-4 antibody generated using NEObody technology, currently in phase 1b/2 clinical trials for advanced/metastatic solid tumors. Other product candidates include ADG206, in phase 1 clinical development for advanced metastatic solid tumors; ADG104, an anti-PD-L1 monoclonal antibody in phase 2 clinical development; and ADG125, a novel anti-CSF-1R mAb in Phase 2 clinical development. Additionally, the company is developing ADG138, a HER2xCD3 POWERbody in preclinical trials for low expressing tumors and resistant/refractory tumors; ADG152, a CD20xCD3 POWERbody in preclinical trials for off-tumor toxicities; ADG153, a masked anti-CD47 IgG1 SAFEbody in preclinical trials for hematologic and solid tumors; and CD28 T-cell engagers, which are anti-CD28 bispecific POWERbody TCEs for solid tumors. Adagene Inc. was incorporated in 2011 and is headquartered in Suzhou, China.

Adagene Inc. (NASDAQ:ADAG) is a publicly traded company in the Life Sciences sector. Wiseek monitors ADAG SEC EDGAR filings and licensed market news in real time, scoring each submission for market-moving significance on a 1–10 scale. Items rated 7 or higher generate instant alerts.

Recent high-impact activity:

  • Adagene Reports H1 2026 Results: $127.9M Cash, Runway into Late 2028, Muzastotug Phase 2 Data Expected 1H 2027
  • Adagene's Muzastotug Shows 31% ORR in MSS CRC, Cash Runway Extended to Late 2028
  • Adagene Reports Strong Unaudited Cash Position of $127.9 Million
  • CEO Peter Luo no longer attributed beneficial ownership of 11.20% stake held by family trust
  • Adagene's Muzastotug Shows Strong Efficacy and Favorable Safety in Combination Therapies for HCC and MSS CRC

Financial Snapshot

Fiscal year ended December 31, 2025
Revenue
$7.67M
Net Income
-$17.61M
Diluted EPS
-$0.30
Op. Cash Flow
-$15.66M
Free Cash Flow
-$15.67M
Operating Income
-$21.44M
Cash & Equivalents
$74.52M
Total Debt
$1.85M
Debt / Equity
0.05×
Net Margin
-229.6%
Shares Outstanding
59.23M sh
Source: 20-F · filed 2026-04-01 · accession 0001104659-26-038612

Dilution Risk

Low risk

Filing-implied dilution signals for ADAG, detected from its recent SEC filings · based on capital-structure filings through 2026-04-02.

1 recent capital raise

Public Offering Priced · Significant Dilution

⚠ A more recent filing has been published for this ticker since this signal was computed; it may not yet be reflected — see the filings below.

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

Insider Transactions

ADAG files as a Foreign Private Issuer (FPI). Under SEC Exchange Act Section 16(a), officers, directors, and 10% owners of FPIs are exempt from Form 4 insider-transaction reporting requirements. Comparable disclosures, when applicable, appear in the company's Form 20-F (annual) or Form 6-K (interim) filings on SEC EDGAR.

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$4.14 +0.09% today
52-week range · as of 2026-08-12 $1.3 – $4.85
Market cap
$276.63M
Volume
278.4K (1.1× avg)
3-mo avg 263.8K
Live data · 2026-08-20 11:55 UTC · Pre-market

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feed ADAG - Latest Insights

ADAG
Aug 12, 2026, 7:30 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $3.80
Real-time Price: $4.14 info
Change: +$0.340 (+9%) info
Market Cap: $276.631M info
ADAG
Aug 12, 2026, 7:30 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $3.80
Real-time Price: $4.14 info
Change: +$0.340 (+9%) info
Market Cap: $276.631M info
ADAG
Jul 06, 2026, 8:00 AM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $4.70
Real-time Price: $4.14 info
Change: -$0.560 (-12%) info
Market Cap: $276.631M info
ADAG
Jun 08, 2026, 6:23 AM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
8
Price at Filing: $3.47
Real-time Price: $4.14 info
Change: +$0.670 (+19%) info
Market Cap: $276.631M info
ADAG
Apr 17, 2026, 4:00 PM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $3.96
Real-time Price: $4.14 info
Change: +$0.180 (+5%) info
Market Cap: $276.631M info
ADAG
Apr 02, 2026, 4:25 PM EDT
Filing Type: 424B5
Importance Score:
8
Price at Filing: $3.99
Real-time Price: $4.14 info
Change: +$0.150 (+4%) info
Market Cap: $276.631M info
ADAG
Apr 02, 2026, 7:11 AM EDT
Filing Type: 6-K
Importance Score:
9
Price at Filing: $3.90
Real-time Price: $4.14 info
Change: +$0.240 (+6%) info
Market Cap: $276.631M info
ADAG
Apr 02, 2026, 7:01 AM EDT
Filing Type: 424B5
Importance Score:
8
Price at Filing: $4.43
Real-time Price: $4.14 info
Change: -$0.290 (-7%) info
Market Cap: $276.631M info
ADAG
Apr 02, 2026, 7:01 AM EDT
Source: GlobeNewswire
Importance Score:
8
Price at Filing: $4.43
Real-time Price: $4.14 info
Change: -$0.290 (-7%) info
Market Cap: $276.631M info
ADAG
Apr 02, 2026, 6:59 AM EDT
Filing Type: 6-K
Importance Score:
9
Price at Filing: $4.43
Real-time Price: $4.14 info
Change: -$0.290 (-7%) info
Market Cap: $276.631M info
ADAG
Apr 01, 2026, 5:15 PM EDT
Filing Type: 20-F
Importance Score:
9
Price at Filing: $4.76
Real-time Price: $4.14 info
Change: -$0.620 (-13%) info
Market Cap: $276.631M info
ADAG
Apr 01, 2026, 5:00 PM EDT
Source: GlobeNewswire
Importance Score:
8
Price at Filing: $4.76
Real-time Price: $4.14 info
Change: -$0.6202 (-13%) info
Market Cap: $276.631M info
ADAG
Jan 23, 2026, 8:00 AM EST
Filing Type: 6-K
Importance Score:
8
Price at Filing: $1.74
Real-time Price: $4.14 info
Change: +$2.40 (+138%) info
Market Cap: $276.631M info
ADAG
Jan 09, 2026, 4:34 PM EST
Filing Type: 424B3
Importance Score:
8
Price at Filing: $1.50
Real-time Price: $4.14 info
Change: +$2.64 (+176%) info
Market Cap: $276.631M info