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Twist Bioscience Corp

corporate_fare Company Profile

Twist Bioscience Corp

TWST·NASDAQ·Life Sciences·CIK 0001581280

Twist Bioscience Corporation develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's core technology manufactures synthetic DNA by "writing" DNA on a silicon chip. This method miniaturizes traditional chemical DNA synthesis reactions, allowing the company to write over 1,000,000 oligonucleotides up to 500 bases through direct synthesis on each silicon chip. This process reduces the estimated amount of chemicals used per gene by 99.8% compared to plate-based synthesis. Twist Bioscience combines its silicon-based DNA writing technology with proprietary software, scalable commercial infrastructure, and an e-commerce platform. From this integrated platform, the company manufactures a broad range of products, including synthetic genes, tools for next generation sequencing (NGS), and sample preparation products. It also provides products and services for drug discovery and development. Twist Bioscience sells its products and services to a global customer base of more than 3,800 customers across various industries, including health care, food/agriculture, industrial chemicals/materials, and academic research.

Twist Bioscience Corp (NASDAQ:TWST) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 32 items for TWST at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-09-21, rated 7/10. Across its 20 most recent items scored 7 or higher, the top rating is 8/10, with 8 rated 8 or above. Recent SEC coverage for TWST spans 4, 144, 8-K, 424B5.

Recent high-impact activity:

  • CEO Emily Leproust Sells $56.3M of Twist Bioscience Stock Under 10b5-1 Plan
  • CEO Emily Leproust Files Form 144 to Sell $44.7M of Twist Bioscience Stock
  • Twist Bioscience Joins Lilly's TuneLab AI Drug Discovery Platform
  • Scorpion Capital Shorts Twist Bioscience, Calls AI Drug Story a 'Speculative Delusion'
  • Anthropic Taps Twist Bioscience to Validate Claude's Drug Design, Stock Surges 17%

Financial Snapshot

Fiscal year ended September 30, 2025
Revenue
$376.57M
Net Income
-$77.67M
Diluted EPS
-$1.30
Op. Cash Flow
-$47.63M
Free Cash Flow
-$75.63M
Gross Profit
$191M
Operating Income
-$136.26M
Cash & Equivalents
$183.05M
Debt / Equity
0.00×
Net Margin
-20.6%
Shares Outstanding
60.63M sh
Source: 10-K · filed 2025-11-17 · accession 0001581280-25-000025

Short Interest & Short Volume

2.82 days to cover

FINRA reported short interest of 10,207,499 shares in TWST as of the October 15, 2026 settlement, a 3.4% decrease from the prior period — about 2.8 days to cover at its recent average daily volume. On November 3, 2026, 52.6% of TWST volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)10,207,499 shares as of October 15, 2026
Change vs prior period▼ 3.4%
Days to cover2.82 at avg daily volume of 3,616,960
Daily short volume (FINRA facilities)52.6% of 804,911 shares on November 3, 2026
5-day average short volume55.3%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Moderate risk

Filing-implied dilution signals for TWST, detected from its recent SEC filings · based on capital-structure filings through 2026-08-04.

1 recent capital raiseATM program1 shelf registration

New Shelf Registration Filed · Establishes $200M At-The-Market Program

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

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$138.69 -1.14% today
52-week range · as of 2026-09-21 $23.3 – $170.23
Market cap
$9.24B
Volume
1.9M (0.7× avg)
3-mo avg 2.9M
Live data · 2026-11-04 02:58 UTC · Market overnight

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feed TWST - Latest Insights

TWST
Sep 21, 2026, 4:05 PM EDT
Filing Type: 4
Importance Score:
7
Price at Filing: $165.83
Real-time Price: $138.69 info
Change: -$27.14 (-16%) info
Market Cap: $9.236B info
TWST
Sep 17, 2026, 4:44 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $155.56
Real-time Price: $138.69 info
Change: -$16.87 (-11%) info
Market Cap: $9.236B info
TWST
Sep 16, 2026, 10:59 AM EDT
Source: Benzinga
Importance Score:
7
Price at Filing: $144.43
Real-time Price: $138.69 info
Change: -$5.74 (-4%) info
Market Cap: $9.236B info
TWST
Aug 19, 2026, 4:11 PM EDT
Source: Benzinga
Importance Score:
7
Price at Filing: $140.00
Real-time Price: $138.69 info
Change: -$1.31 (-0.93%) info
Market Cap: $9.236B info
TWST
Aug 19, 2026, 12:31 PM EDT
Source: Dow Jones Newswires
Importance Score:
8
Price at Filing: $136.04
Real-time Price: $138.69 info
Change: +$2.65 (+2%) info
Market Cap: $9.236B info
TWST
Aug 10, 2026, 7:37 AM EDT
Source: Wiseek News
Importance Score:
7
Price at Filing: $118.00
Real-time Price: $138.69 info
Change: +$20.69 (+18%) info
Market Cap: $9.236B info
TWST
Aug 05, 2026, 5:27 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $115.00
Real-time Price: $138.69 info
Change: +$23.69 (+21%) info
Market Cap: $9.236B info
TWST
Aug 04, 2026, 11:45 PM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $97.00
Real-time Price: $138.69 info
Change: +$41.69 (+43%) info
Market Cap: $9.236B info
TWST
Aug 04, 2026, 5:19 PM EDT
Filing Type: 424B5
Importance Score:
8
Price at Filing: $97.94
Real-time Price: $138.69 info
Change: +$40.75 (+42%) info
Market Cap: $9.236B info
TWST
Aug 04, 2026, 4:01 PM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $98.01
Real-time Price: $138.69 info
Change: +$40.68 (+42%) info
Market Cap: $9.236B info
TWST
Aug 03, 2026, 4:10 PM EDT
Filing Type: 10-Q
Importance Score:
8
Price at Filing: $101.06
Real-time Price: $138.69 info
Change: +$37.63 (+37%) info
Market Cap: $9.236B info
TWST
Aug 03, 2026, 7:21 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $90.50
Real-time Price: $138.69 info
Change: +$48.19 (+53%) info
Market Cap: $9.236B info
TWST
Jun 24, 2026, 2:44 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $91.50
Real-time Price: $138.69 info
Change: +$47.19 (+52%) info
Market Cap: $9.236B info
TWST
Jun 18, 2026, 6:32 PM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $83.36
Real-time Price: $138.69 info
Change: +$55.33 (+66%) info
Market Cap: $9.236B info
TWST
Jun 18, 2026, 4:09 PM EDT
Filing Type: S-3ASR
Importance Score:
7
Price at Filing: $87.42
Real-time Price: $138.69 info
Change: +$51.27 (+59%) info
Market Cap: $9.236B info
TWST
Jun 15, 2026, 2:56 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $81.70
Real-time Price: $138.69 info
Change: +$56.99 (+70%) info
Market Cap: $9.236B info
TWST
May 29, 2026, 1:58 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $69.22
Real-time Price: $138.69 info
Change: +$69.47 (+100%) info
Market Cap: $9.236B info
TWST
May 28, 2026, 4:21 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $69.03
Real-time Price: $138.69 info
Change: +$69.66 (+101%) info
Market Cap: $9.236B info
TWST
May 27, 2026, 4:26 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $64.17
Real-time Price: $138.69 info
Change: +$74.52 (+116%) info
Market Cap: $9.236B info
TWST
May 04, 2026, 4:31 PM EDT
Source: Wiseek News
Importance Score:
7
Price at Filing: $56.20
Real-time Price: $138.69 info
Change: +$82.49 (+147%) info
Market Cap: $9.236B info
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