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TWST
NASDAQ Life Sciences

Twist Bioscience Q3 Revenue Jumps 23% to $118M, But Losses Widen; CEO Adopts 10b5-1 Plan

Arie Shkolnikov · Analysis by Wiseek AI
More coverage: Diagnostics & Research Stocks · Healthcare
Sentiment info
Negative
Importance info
8
Price
$101.06
Mkt Cap
$6.293B
52W Low
$23.3
52W High
$105.47
52W Position info
334% above low
Off High info
4.2% below high
Rel. Volume info
1.7× avg
Market data snapshot near publication time

TWST has more than doubled off its 52-week low of $23.3.

Summary

Twist Bioscience reported Q3 FY2026 revenue of $118.4M (+23% YoY) but swung to a net loss of $35.1M. The CEO, President, and a director adopted 10b5-1 plans for potential sales of up to 720,906 shares, adding to recent insider selling.


Key Events · Earnings and Guidance · TWST

  • Revenue Growth, But Losses Widen

    Q3 revenue rose 23% to $118.4M, but the company posted a net loss of $35.1M vs. a $20.4M profit a year ago. Nine-month net loss widened to $109.6M from $50.5M.

  • Gross Margin Pressure

    Gross margin declined to 52.8% from 53.4% in Q3 FY2025, primarily due to customer mix, despite higher revenues.

  • Cash Burn Accelerates

    Cash, equivalents, and short-term investments fell to $166.8M from $232.4M at fiscal year-end. Operating cash burn was $41.3M for nine months, up from $35.8M.

  • CEO and Insiders Adopt 10b5-1 Plans

    CEO Emily Leproust adopted a plan to sell up to 624,134 shares; President Patrick Finn up to 78,355 shares; Director Robert Chess up to 18,417 shares. This follows $12.6M in insider sales over the past 90 days.


Analysis · TWST · Life Sciences

Record quarterly revenue of $118.4 million—a 23% year-over-year surge—underscores robust demand in DNA synthesis and NGS applications. Yet the top-line strength was overshadowed by a swing to a net loss of $35.1 million, compared with a profit a year ago, pushing the nine-month loss to $109.6 million. Gross margin slipped to 52.8% from 53.4%, pressured by customer mix. Cash reserves contracted to $166.8 million from $232.4 million at fiscal year-end, though management asserts sufficient liquidity for at least 12 months. In a separate development, the CEO, President, and a director adopted 10b5-1 trading plans covering up to 720,906 shares combined, extending a pattern of insider selling that has exceeded $12.6 million in the past 90 days. While the $200 million ATM program remains untapped, the shelf registration and insider selling plans create an overhang.

At the time of this filing, TWST was trading at $101.06 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $6.3B. The 52-week trading range was $23.30 to $105.47. This filing was assessed with negative market sentiment and an importance score of 8 out of 10.

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TWST - Latest Insights

TWST
Aug 03, 2026, 7:21 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $90.50
Real-time Price: $101.06 info
Change: +$10.56 (+12%) info
Market Cap: $6.293B info
TWST
Jun 24, 2026, 2:44 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $91.50
Real-time Price: $101.06 info
Change: +$9.56 (+10%) info
Market Cap: $6.293B info
TWST
Jun 18, 2026, 6:32 PM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $83.36
Real-time Price: $101.06 info
Change: +$17.70 (+21%) info
Market Cap: $6.293B info
TWST
Jun 18, 2026, 4:09 PM EDT
Filing Type: S-3ASR
Importance Score:
7
Price at Filing: $87.42
Real-time Price: $101.06 info
Change: +$13.64 (+16%) info
Market Cap: $6.293B info
TWST
Jun 15, 2026, 2:56 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $81.70
Real-time Price: $101.06 info
Change: +$19.36 (+24%) info
Market Cap: $6.293B info