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XORTX Therapeutics Inc.

corporate_fare Company Profile

XORTX Therapeutics Inc.

XRTX·NASDAQ·Life Sciences·CIK 0001729214

XORTX Therapeutics Inc. is a late-stage clinical pharmaceutical company focused on developing and commercializing treatments for diseases linked to high uric acid levels in Canada. The company is developing several therapies: XRx-026, which is in Phase III clinical trials for treating gout; XRx-008, currently in Phase II for autosomal dominant polycystic kidney disease; and XRx-101, also in Phase II, for acute kidney injury resulting from respiratory virus infections, including sepsis and coronavirus. Additionally, XRX-225 is in the preclinical stage for treating type 2 diabetic nephropathy. XORTX Therapeutics Inc. also has a program called VB4-P5, which aims to treat and prevent kidney fibrosis. The company operates from Calgary, Canada.

XORTX Therapeutics Inc. (NASDAQ:XRTX) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 25 items for XRTX at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-09-18, rated 7/10. Across its 20 most recent items scored 7 or higher, the top rating is 9/10, with 14 rated 8 or above. Recent SEC coverage for XRTX spans 6-K, 424B4, 20-F.

Recent high-impact activity:

  • XORTX Sets Q4 2026 FDA IND Submission for Gout Drug XORLO™, Targets NDA in About a Year
  • XORTX Targets Q4 FDA Filing for Gout Drug, Sees $700M Market
  • XORTX Re-Engages IR Agency with $2.5M Non-Refundable Fee After Delisting
  • XORTX Recovers $2.5M from Terminated IR Program, Discloses $240K Acquisition Fee
  • XORTX Reports $2.5M Loss, Going Concern Warning, and Material Weakness

Financial Snapshot

Fiscal year ended December 31, 2025
Net Income
-$2.66M
Diluted EPS
-$0.56
Op. Cash Flow
-$2.77M
Cash & Equivalents
$864.51K
Debt / Equity
0.00×
Shares Outstanding
6.96M sh
Source: 20-F · filed 2026-03-20 · accession 0001104659-26-032775

Short Interest & Short Volume

1.00 days to cover

FINRA reported short interest of 76,755 shares in XRTX as of the September 15, 2026 settlement, a 424.5% increase from the prior period — about 1.0 days to cover at its recent average daily volume. On October 2, 2026, 5.4% of XRTX volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)76,755 shares as of September 15, 2026
Change vs prior period▲ 424.5%
Days to cover1.00 at avg daily volume of 367,812
Daily short volume (FINRA facilities)5.4% of 1,919 shares on October 2, 2026
5-day average short volume21.7%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Low risk

Filing-implied dilution signals for XRTX, detected from its recent SEC filings · based on capital-structure filings through 2026-05-19.

1 recent capital raise

Public Offering Finalized · Significant Dilution

⚠ A more recent filing has been published for this ticker since this signal was computed; it may not yet be reflected — see the filings below.

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

Insider Transactions

XRTX files as a Foreign Private Issuer (FPI). Under SEC Exchange Act Section 16(a), officers, directors, and 10% owners of FPIs are exempt from Form 4 insider-transaction reporting requirements. Comparable disclosures, when applicable, appear in the company's Form 20-F (annual) or Form 6-K (interim) filings on SEC EDGAR.

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$1.73
52-week range · as of 2026-09-18 $1.59 – $7.05
Market cap
$3.11M
Volume
4.5K (0.0× avg)
3-mo avg 467.1K
Live data · 2026-10-05 02:48 UTC · Market closed

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feed XRTX - Latest Insights

XRTX
Sep 18, 2026, 8:05 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.76
Real-time Price: $1.73 info
Change: -$0.0344 (-2%) info
Market Cap: $3.114M info
XRTX
Sep 18, 2026, 8:05 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $1.68
Real-time Price: $1.73 info
Change: +$0.050 (+3%) info
Market Cap: $3.114M info
XRTX
Sep 04, 2026, 8:51 AM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $2.39
Real-time Price: $1.73 info
Change: -$0.660 (-28%) info
Market Cap: $3.114M info
XRTX
Aug 28, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
9
Price at Filing: $2.44
Real-time Price: $1.73 info
Change: -$0.710 (-29%) info
Market Cap: $3.114M info
XRTX
Aug 17, 2026, 6:00 AM EDT
Filing Type: 6-K
Importance Score:
9
Price at Filing: $2.19
Real-time Price: $1.73 info
Change: -$0.460 (-21%) info
Market Cap: $3.114M info
XRTX
Jun 15, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $2.06
Real-time Price: $1.73 info
Change: -$0.3339 (-16%) info
Market Cap: $3.114M info
XRTX
Jun 12, 2026, 5:00 PM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $2.18
Real-time Price: $1.73 info
Change: -$0.450 (-21%) info
Market Cap: $3.114M info
XRTX
May 19, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
9
Price at Filing: $2.53
Real-time Price: $1.73 info
Change: -$0.800 (-32%) info
Market Cap: $3.114M info
XRTX
May 19, 2026, 7:00 AM EDT
Source: GlobeNewswire
Importance Score:
9
Price at Filing: $2.53
Real-time Price: $1.73 info
Change: -$0.800 (-32%) info
Market Cap: $3.114M info
XRTX
May 15, 2026, 10:29 AM EDT
Filing Type: 424B4
Importance Score:
9
Price at Filing: $2.60
Real-time Price: $1.73 info
Change: -$0.870 (-33%) info
Market Cap: $3.114M info
XRTX
May 14, 2026, 9:09 AM EDT
Filing Type: 6-K
Importance Score:
9
Price at Filing: $2.04
Real-time Price: $1.73 info
Change: -$0.310 (-15%) info
Market Cap: $3.114M info
XRTX
May 08, 2026, 4:30 PM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $2.79
Real-time Price: $1.73 info
Change: -$1.06 (-38%) info
Market Cap: $3.114M info
XRTX
Apr 21, 2026, 10:07 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $2.98
Real-time Price: $1.73 info
Change: -$1.25 (-42%) info
Market Cap: $3.114M info
XRTX
Apr 13, 2026, 5:00 PM EDT
Source: GlobeNewswire
Importance Score:
9
Price at Filing: $3.43
Real-time Price: $1.73 info
Change: -$1.70 (-50%) info
Market Cap: $3.114M info
XRTX
Mar 26, 2026, 5:44 PM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $0.400
Real-time Price: $1.73 info
Change: Reverse Stock Split info
Market Cap: $3.114M info
XRTX
Mar 25, 2026, 8:15 PM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $0.340
Real-time Price: $1.73 info
Change: Reverse Stock Split info
Market Cap: $3.114M info
XRTX
Mar 24, 2026, 5:00 PM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $0.3611
Real-time Price: $1.73 info
Change: Reverse Stock Split info
Market Cap: $3.114M info
XRTX
Mar 20, 2026, 5:00 PM EDT
Filing Type: 20-F
Importance Score:
9
Price at Filing: $0.389
Real-time Price: $1.73 info
Change: Reverse Stock Split info
Market Cap: $3.114M info
XRTX
Mar 18, 2026, 8:40 PM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $0.4313
Real-time Price: $1.73 info
Change: Reverse Stock Split info
Market Cap: $3.114M info
XRTX
Mar 13, 2026, 11:22 AM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $0.39725
Real-time Price: $1.73 info
Change: Reverse Stock Split info
Market Cap: $3.114M info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets