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Tiziana Life Sciences Ltd

corporate_fare Company Profile

Tiziana Life Sciences Ltd

TLSA·NASDAQ·Life Sciences·CIK 0001723069

Tiziana Life Sciences Ltd. is a clinical-stage biotechnology company listed on NASDAQ under the ticker TLSA. The company specializes in developing therapies for neurodegenerative and neuroinflammatory diseases. Its clinical pipeline includes drug assets targeting Non-Active Secondary Progressive Multiple Sclerosis, Multiple System Atrophy, Alzheimer's, and Amyotrophic lateral sclerosis. Tiziana Life Sciences Ltd. was originally incorporated in England and Wales on February 11, 1998, and changed its name to Tiziana Life Sciences plc in April 2014 following the acquisition of Tiziana Pharma Limited. On October 20, 2021, the company completed a reorganization, establishing Tiziana Life Sciences Ltd., a Bermuda-incorporated company, as the ultimate parent company. Its registered office is in Hamilton, Bermuda.

Tiziana Life Sciences Ltd (NASDAQ:TLSA) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 25 items for TLSA at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-09-30, rated 7/10. Across its 20 most recent items scored 7 or higher, the top rating is 8/10, with 4 rated 8 or above. Recent SEC coverage for TLSA spans 6-K, 4, 20-F.

Recent high-impact activity:

  • Tiziana Seeks FDA Orphan Drug Designation for Intranasal Foralumab in MSA
  • Tiziana Files for FDA Orphan Drug Designation for Intranasal Foralumab in MSA
  • Tiziana Doses First Three Patients in Phase 2a ALS BANYAN Trial of Intranasal Foralumab
  • Tiziana Doses First ALS Patients in Phase 2a BANYAN Trial of Intranasal Foralumab
  • Tiziana Completes Last Patient Visit in Phase 2a INFORM-MS Trial; Topline Data Due October

Financial Snapshot

Fiscal year ended December 31, 2025
Net Income
-$18.43M
Diluted EPS
-$0.16
Op. Cash Flow
-$12.85M
Free Cash Flow
-$12.87M
Operating Income
-$21.13M
Cash & Equivalents
$4.01M
Debt / Equity
0.00×
Shares Outstanding
2.1M sh
Source: 20-F · filed 2026-05-01 · accession 0001213900-26-051015

Short Interest & Short Volume

3.54 days to cover

FINRA reported short interest of 1,733,862 shares in TLSA as of the September 15, 2026 settlement, a 2.0% increase from the prior period — about 3.5 days to cover at its recent average daily volume. On October 2, 2026, 49.4% of TLSA volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)1,733,862 shares as of September 15, 2026
Change vs prior period▲ 2.0%
Days to cover3.54 at avg daily volume of 489,911
Daily short volume (FINRA facilities)49.4% of 273,173 shares on October 2, 2026
5-day average short volume49.2%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Low risk

Filing-implied dilution signals for TLSA, detected from its recent SEC filings.

ATM program

Auditors Issue Going Concern Warning · Secured $8.6M in Registered Direct Offering

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

Insider Transactions

TLSA files as a Foreign Private Issuer (FPI). Under SEC Exchange Act Section 16(a), officers, directors, and 10% owners of FPIs are exempt from Form 4 insider-transaction reporting requirements. Comparable disclosures, when applicable, appear in the company's Form 20-F (annual) or Form 6-K (interim) filings on SEC EDGAR.

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$1.12
52-week range · as of 2026-09-30 $0.7615 – $2.33
Market cap
$143.71M
Volume
436.8K (0.7× avg)
3-mo avg 642K
Live data · 2026-10-05 03:11 UTC · Market closed

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feed TLSA - Latest Insights

TLSA
Sep 30, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.00
Real-time Price: $1.12 info
Change: +$0.120 (+12%) info
Market Cap: $143.706M info
TLSA
Sep 30, 2026, 7:00 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $1.01
Real-time Price: $1.12 info
Change: +$0.110 (+11%) info
Market Cap: $143.706M info
TLSA
Sep 28, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.00
Real-time Price: $1.12 info
Change: +$0.120 (+12%) info
Market Cap: $143.706M info
TLSA
Sep 28, 2026, 7:00 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $1.00
Real-time Price: $1.12 info
Change: +$0.120 (+12%) info
Market Cap: $143.706M info
TLSA
Sep 21, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $0.9051
Real-time Price: $1.12 info
Change: +$0.2149 (+24%) info
Market Cap: $143.706M info
TLSA
Sep 17, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $0.8184
Real-time Price: $1.12 info
Change: +$0.3016 (+37%) info
Market Cap: $143.706M info
TLSA
Sep 17, 2026, 7:00 AM EDT
Source: Wiseek News
Importance Score:
7
Price at Filing: $0.8169
Real-time Price: $1.12 info
Change: +$0.3031 (+37%) info
Market Cap: $143.706M info
TLSA
Aug 06, 2026, 9:30 AM EDT
Filing Type: 4
Importance Score:
8
Price at Filing: $0.990
Real-time Price: $1.12 info
Change: +$0.130 (+13%) info
Market Cap: $143.706M info
TLSA
Aug 06, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.01
Real-time Price: $1.12 info
Change: +$0.110 (+11%) info
Market Cap: $143.706M info
TLSA
Aug 04, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $0.9536
Real-time Price: $1.12 info
Change: +$0.1664 (+17%) info
Market Cap: $143.706M info
TLSA
Jul 31, 2026, 1:32 PM EDT
Source: Benzinga
Importance Score:
7
Price at Filing: $1.03
Real-time Price: $1.12 info
Change: +$0.0902 (+9%) info
Market Cap: $143.706M info
TLSA
Jul 31, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $0.9526
Real-time Price: $1.12 info
Change: +$0.1674 (+18%) info
Market Cap: $143.706M info
TLSA
Jun 25, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.12
Real-time Price: $1.12 info
Change: $0 (0%) info
Market Cap: $143.706M info
TLSA
May 21, 2026, 11:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.68
Real-time Price: $1.12 info
Change: -$0.555 (-33%) info
Market Cap: $143.706M info
TLSA
May 19, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.37
Real-time Price: $1.12 info
Change: -$0.250 (-18%) info
Market Cap: $143.706M info
TLSA
May 14, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
8
Price at Filing: $1.55
Real-time Price: $1.12 info
Change: -$0.4301 (-28%) info
Market Cap: $143.706M info
TLSA
May 01, 2026, 5:00 PM EDT
Filing Type: 20-F
Importance Score:
8
Price at Filing: $1.34
Real-time Price: $1.12 info
Change: -$0.220 (-16%) info
Market Cap: $143.706M info
TLSA
Apr 16, 2026, 7:00 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $1.29
Real-time Price: $1.12 info
Change: -$0.1696 (-13%) info
Market Cap: $143.706M info
TLSA
Apr 01, 2026, 7:00 AM EDT
Filing Type: 6-K
Importance Score:
7
Price at Filing: $1.22
Real-time Price: $1.12 info
Change: -$0.100 (-8%) info
Market Cap: $143.706M info
TLSA
Feb 25, 2026, 7:00 AM EST
Filing Type: 6-K
Importance Score:
8
Price at Filing: $1.34
Real-time Price: $1.12 info
Change: -$0.2157 (-16%) info
Market Cap: $143.706M info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets