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Summit Therapeutics Inc.

corporate_fare Company Profile

Summit Therapeutics Inc.

SMMT·NASDAQ·Life Sciences·CIK 0001599298

Summit Therapeutics Inc. is a biopharmaceutical company that discovers, develops, and commercializes medicinal therapies. The company aims to improve quality of life, increase potential duration of life, and address serious unmet medical needs. Its pipeline of product candidates focuses on oncology. Summit's lead development candidate is ivonescimab, a bispecific antibody designed to combine immunotherapy (PD-1 blockade) with anti-angiogenesis (anti-VEGF) effects in a single molecule. On December 5, 2022, Summit entered into a License Agreement with Akeso, Inc. and its affiliates, through which it in-licensed intellectual property rights for ivonescimab. This agreement granted Summit rights to develop and commercialize ivonescimab in the United States, Canada, Europe, and Japan. The transaction closed in January 2023. On June 3, 2024, Summit amended the License Agreement with Akeso to expand its territories to include Latin America (Mexico and all countries in Central and South America), the Middle East, and Africa. The company's operations are currently focused on the development of ivonescimab.

Summit Therapeutics Inc. (NASDAQ:SMMT) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 47 items for SMMT at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-10-25, rated 7/10. Across its 20 most recent items scored 7 or higher, the top rating is 9/10, with 15 rated 8 or above. Recent SEC coverage for SMMT spans DEF 14A, PRE 14A, 8-K, 10-Q.

Recent high-impact activity:

  • Ivonescimab Beats Durvalumab in Biliary Tract Cancer: OS 14.9 vs 12.1 Months
  • Summit Seeks 2B Authorized Shares to Cover AstraZeneca Conversion; Vote Nov 4
  • Summit Seeks Shareholder Approval to Double Authorized Shares for AstraZeneca Conversion
  • Summit Partners with AstraZeneca and Daiichi Sankyo on Ivonescimab-Datroway Combo
  • AstraZeneca Invests $2B in Summit Therapeutics at $18.36/Share Premium

Financial Snapshot

Fiscal year ended December 31, 2025
Net Income
-$1.08B
Diluted EPS
-$1.44
Op. Cash Flow
-$322.93M
Free Cash Flow
-$323.59M
Cash & Equivalents
$225.27M
Debt / Equity
0.00×
Shares Outstanding
775.37M sh
Source: 10-K · filed 2026-02-23 · accession 0001599298-26-000015

Short Interest & Short Volume

7.02 days to cover

FINRA reported short interest of 40,896,653 shares in SMMT as of the October 15, 2026 settlement, a 0.6% decrease from the prior period — about 7.0 days to cover at its recent average daily volume. On October 30, 2026, 49.0% of SMMT volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)40,896,653 shares as of October 15, 2026
Change vs prior period▼ 0.6%
Days to cover7.02 at avg daily volume of 5,823,946
Daily short volume (FINRA facilities)49.0% of 1,332,276 shares on October 30, 2026
5-day average short volume51.2%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Moderate risk

Filing-implied dilution signals for SMMT, detected from its recent SEC filings · based on capital-structure filings through 2026-09-29.

2 recent capital raisesATM program1 shelf registration

ATM Program Formalized · Dilution Details

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

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$15.98 -0.32% today
52-week range · as of 2026-10-19 $12.07 – $29.23
Market cap
$12.82B
Volume
3.5M (0.6× avg)
3-mo avg 6.2M
Live data · 2026-11-02 02:38 UTC · Market closed

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feed SMMT - Latest Insights

SMMT
Oct 25, 2026, 11:52 AM EDT
Source: BusinessWire
Importance Score:
7
Price at Filing: $15.51
Real-time Price: $15.98 info
Change: +$0.467 (+3%) info
Market Cap: $12.82B info
SMMT
Oct 19, 2026, 7:01 AM EDT
Filing Type: DEF 14A
Importance Score:
7
Price at Filing: $14.75
Real-time Price: $15.98 info
Change: +$1.23 (+8%) info
Market Cap: $12.82B info
SMMT
Oct 06, 2026, 5:03 PM EDT
Filing Type: PRE 14A
Importance Score:
7
Price at Filing: $17.29
Real-time Price: $15.98 info
Change: -$1.31 (-8%) info
Market Cap: $12.82B info
SMMT
Oct 02, 2026, 2:30 AM EDT
Source: BusinessWire
Importance Score:
8
Updated Oct 2, 6:39 AM ET — The collaboration will evaluate Datroway with ivonescimab across multiple tumor types, including lung and breast cancers.
Price at Filing: $16.79
Real-time Price: $15.98 info
Change: -$0.8115 (-5%) info
Market Cap: $12.82B info
SMMT
Sep 28, 2026, 9:39 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $18.58
Real-time Price: $15.98 info
Change: -$2.60 (-14%) info
Market Cap: $12.82B info
SMMT
Sep 15, 2026, 8:44 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $18.30
Real-time Price: $15.98 info
Change: -$2.32 (-13%) info
Market Cap: $12.82B info
SMMT
Sep 14, 2026, 8:37 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $18.15
Real-time Price: $15.98 info
Change: -$2.17 (-12%) info
Market Cap: $12.82B info
SMMT
Sep 13, 2026, 7:00 AM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $17.70
Real-time Price: $15.98 info
Change: -$1.72 (-10%) info
Market Cap: $12.82B info
SMMT
Sep 03, 2026, 9:21 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $15.27
Real-time Price: $15.98 info
Change: +$0.7085 (+5%) info
Market Cap: $12.82B info
SMMT
Sep 02, 2026, 5:41 PM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $15.00
Real-time Price: $15.98 info
Change: +$0.9769 (+7%) info
Market Cap: $12.82B info
SMMT
Aug 26, 2026, 1:46 PM EDT
Source: Benzinga
Importance Score:
8
Price at Filing: $14.00
Real-time Price: $15.98 info
Change: +$1.98 (+14%) info
Market Cap: $12.82B info
SMMT
Aug 26, 2026, 9:17 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $14.00
Real-time Price: $15.98 info
Change: +$1.98 (+14%) info
Market Cap: $12.82B info
SMMT
Aug 25, 2026, 6:00 PM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $13.25
Real-time Price: $15.98 info
Change: +$2.73 (+21%) info
Market Cap: $12.82B info
SMMT
Aug 25, 2026, 12:33 PM EDT
Source: Benzinga
Importance Score:
8
Price at Filing: $13.31
Real-time Price: $15.98 info
Change: +$2.67 (+20%) info
Market Cap: $12.82B info
SMMT
Aug 12, 2026, 9:22 AM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $15.31
Real-time Price: $15.98 info
Change: +$0.6685 (+4%) info
Market Cap: $12.82B info
SMMT
Aug 05, 2026, 7:32 AM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $13.98
Real-time Price: $15.98 info
Change: +$2.00 (+14%) info
Market Cap: $12.82B info
SMMT
Jul 23, 2026, 4:34 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $14.68
Real-time Price: $15.98 info
Change: +$1.30 (+9%) info
Market Cap: $12.82B info
SMMT
Jul 23, 2026, 4:08 PM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $14.21
Real-time Price: $15.98 info
Change: +$1.77 (+12%) info
Market Cap: $12.82B info
SMMT
Jul 23, 2026, 4:07 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $14.52
Real-time Price: $15.98 info
Change: +$1.46 (+10%) info
Market Cap: $12.82B info
SMMT
Jul 22, 2026, 7:10 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $14.48
Real-time Price: $15.98 info
Change: +$1.50 (+10%) info
Market Cap: $12.82B info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets