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Odyssey Therapeutics, Inc.

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Odyssey Therapeutics, Inc.

ODTX·NASDAQ·Life Sciences·CIK 0001882782

Odyssey Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing medicines for autoimmune and inflammatory diseases. The company's pipeline features several drug candidates. OD-001 is an oral small molecule inhibitor of receptor-interacting protein kinase 2, currently in a Phase 2a trial for the treatment of ulcerative colitis. OD-002 is an oral small molecule SLC15A4 inhibitor, designed to block the activation of interferon regulatory factor 5 (IRF5) which mediates pathogenic inflammatory responses driven by TLR7/8/9. Another candidate, OD-003, is a protein therapeutic designed to selectively agonize tumor necrosis factor receptor 2 on Treg cells. The pipeline also includes a TSLP/IL-33 bispecific antagonist, an oral small molecule interleukin-1 receptor–associated kinase 4 scaffolding inhibitor, and a small molecule inhibitor of IRF5. Odyssey Therapeutics, Inc. was incorporated in 2021 and is headquartered in Boston, Massachusetts.

Odyssey Therapeutics, Inc. (NASDAQ:ODTX) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 16 items for ODTX at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-09-08, rated 7/10. Across its 16 most recent items scored 7 or higher, the top rating is 9/10, with 11 rated 8 or above. Recent SEC coverage for ODTX spans 8-K, 10-Q, SCHEDULE 13D, 424B4.

Recent high-impact activity:

  • Pipeline Update: OD-002 CTA Filing on Track for H2 2026, Detailed OD-001 Phase 2a Results
  • Odyssey Therapeutics Partners with Evotec on AI-Driven Autoimmune Drug Discovery
  • Odyssey Therapeutics Q2 2026: Cash Runway Extended to H2 2028, OD-001 Phase 2a Costs Drive R&D Increase
  • Odyssey Q2 2026: $433M Cash and Pipeline Progress, with OD-001 Data Headed to UEG Week
  • Odyssey Therapeutics Posts Q2 Loss, Cash Runway Into 2028; Key Trials on Track

Short Interest & Short Volume

10.78 days to cover

FINRA reported short interest of 2,208,686 shares in ODTX as of the September 15, 2026 settlement, unchanged from the prior period — about 10.8 days to cover at its recent average daily volume. On October 2, 2026, 60.0% of ODTX volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)2,208,686 shares as of September 15, 2026
Change vs prior period 0.0%
Days to cover10.78 at avg daily volume of 204,876
Daily short volume (FINRA facilities)60.0% of 66,218 shares on October 2, 2026
5-day average short volume78.4%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Low risk

Filing-implied dilution signals for ODTX, detected from its recent SEC filings · based on capital-structure filings through 2026-05-08.

1 recent capital raise

Initial Public Offering (IPO) Priced · Concurrent Private Placement

⚠ A more recent filing has been published for this ticker since this signal was computed; it may not yet be reflected — see the filings below.

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

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$20.73
52-week range · as of 2026-09-08 $15.1 – $29.05
Market cap
$996.01M
Volume
192.5K (0.6× avg)
3-mo avg 333.6K
Live data · 2026-10-05 04:07 UTC · Market overnight

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feed ODTX - Latest Insights

ODTX
Sep 08, 2026, 7:10 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $26.97
Real-time Price: $20.73 info
Change: -$6.24 (-23%) info
Market Cap: $996.013M info
ODTX
Aug 06, 2026, 1:30 AM EDT
Source: EQS
Importance Score:
7
Price at Filing: $21.99
Real-time Price: $20.73 info
Change: -$1.26 (-6%) info
Market Cap: $996.013M info
ODTX
Aug 05, 2026, 7:00 PM EDT
Filing Type: 10-Q
Importance Score:
7
Price at Filing: $21.99
Real-time Price: $20.73 info
Change: -$1.26 (-6%) info
Market Cap: $996.013M info
ODTX
Aug 04, 2026, 7:00 AM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $18.13
Real-time Price: $20.73 info
Change: +$2.60 (+14%) info
Market Cap: $996.013M info
ODTX
Aug 04, 2026, 7:00 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $18.13
Real-time Price: $20.73 info
Change: +$2.60 (+14%) info
Market Cap: $996.013M info
ODTX
Jun 23, 2026, 8:45 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $18.72
Real-time Price: $20.73 info
Change: +$2.01 (+11%) info
Market Cap: $996.013M info
ODTX
Jun 17, 2026, 4:45 PM EDT
Filing Type: 10-Q
Importance Score:
8
Price at Filing: $18.48
Real-time Price: $20.73 info
Change: +$2.25 (+12%) info
Market Cap: $996.013M info
ODTX
Jun 17, 2026, 4:45 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $18.48
Real-time Price: $20.73 info
Change: +$2.25 (+12%) info
Market Cap: $996.013M info
ODTX
Jun 17, 2026, 4:15 PM EDT
Source: GlobeNewswire
Importance Score:
9
Price at Filing: $18.48
Real-time Price: $20.73 info
Change: +$2.25 (+12%) info
Market Cap: $996.013M info
ODTX
May 18, 2026, 6:29 PM EDT
Filing Type: SCHEDULE 13D
Importance Score:
8
Price at Filing: $17.39
Real-time Price: $20.73 info
Change: +$3.34 (+19%) info
Market Cap: $996.013M info
ODTX
May 18, 2026, 4:06 PM EDT
Filing Type: SCHEDULE 13D
Importance Score:
8
Price at Filing: $17.39
Real-time Price: $20.73 info
Change: +$3.34 (+19%) info
Market Cap: $996.013M info
ODTX
May 15, 2026, 4:08 PM EDT
Filing Type: SCHEDULE 13D
Importance Score:
8
Price at Filing: $17.62
Real-time Price: $20.73 info
Change: +$3.11 (+18%) info
Market Cap: $996.013M info
ODTX
May 15, 2026, 2:58 PM EDT
Filing Type: SCHEDULE 13D
Importance Score:
8
Price at Filing: $17.59
Real-time Price: $20.73 info
Change: +$3.14 (+18%) info
Market Cap: $996.013M info
ODTX
May 11, 2026, 4:30 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $17.45
Real-time Price: $20.73 info
Change: +$3.28 (+19%) info
Market Cap: $996.013M info
ODTX
May 08, 2026, 4:45 PM EDT
Filing Type: 424B4
Importance Score:
9
Price at Filing: $16.33
Real-time Price: $20.73 info
Change: +$4.40 (+27%) info
Market Cap: $996.013M info
ODTX
May 07, 2026, 9:12 PM EDT
Source: Dow Jones Newswires
Importance Score:
8
Price at Filing: N/A
Real-time Price: $20.73 info
Change: N/A info
Market Cap: $996.013M info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets