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Nautilus Biotechnology, Inc.

corporate_fare Company Profile

Nautilus Biotechnology, Inc.

NAUT·NASDAQ·Industrial Applications And Services·CIK 0001808805

Nautilus Biotechnology, Inc. is a development stage life sciences company focused on creating a platform technology to quantify and understand the proteome in the United States. The company is developing the Nautilus Voyager Platform, an end-to-end solution that includes instruments, reagents, consumables, and software analysis. Its offerings include the Nautilus Voyager Instrument, a high-resolution optical imaging system with integrated fluidics and liquid handling. This system deposits protein libraries onto a flow cell and rapidly processes labeled multi-affinity reagent binding and imaging cycles to decode and quantify proteins in biological samples. Nautilus Biotechnology also provides single-molecule library preparation kits, flow cells, affinity reagents, and instrument run buffers for multi-cycle analysis runs. The company has research collaboration agreements with Genentech, Buck Institute, Allen Institute, Cornell University, the Qatar Foundation, and the Michael J. Fox Foundation. Nautilus Biotechnology, Inc. was founded in 2016 and is headquartered in Seattle, Washington.

Nautilus Biotechnology, Inc. (NASDAQ:NAUT) is a publicly traded company in the Industrial Applications And Services sector. Wiseek has independently scored 14 items for NAUT at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-09-11, rated 7/10. Across its 14 most recent items scored 7 or higher, the top rating is 8/10, with 7 rated 8 or above. Recent SEC coverage for NAUT spans SCHEDULE 13D/A, 10-Q, 8-K, 10-K.

Recent high-impact activity:

  • Andreessen Horowitz Sells Another 1.4M Nautilus Shares, Drops Below 5% Stake
  • Andreessen Horowitz Sells Another 1.25M Nautilus Shares, Stake Falls to 6.0%
  • Perceptive Advisors Discloses 9.1% Stake in Nautilus Biotechnology
  • Nautilus Posts First Revenue but Indefinitely Delays Broadscale Assay
  • Nautilus Posts First Revenue, Narrows Loss; Delays Broadscale Assay

Financial Snapshot

Fiscal year ended December 31, 2025
Net Income
-$59M
Diluted EPS
-$0.47
Op. Cash Flow
-$50.7M
Free Cash Flow
-$51.97M
Cash & Equivalents
$12.39M
Debt / Equity
0.00×
Shares Outstanding
126.47M sh
Source: 10-K · filed 2026-02-26 · accession 0001808805-26-000011

Short Interest & Short Volume

3.24 days to cover

FINRA reported short interest of 4,082,014 shares in NAUT as of the September 15, 2026 settlement, a 7.0% increase from the prior period — about 3.2 days to cover at its recent average daily volume. On October 2, 2026, 57.4% of NAUT volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)4,082,014 shares as of September 15, 2026
Change vs prior period▲ 7.0%
Days to cover3.24 at avg daily volume of 1,259,682
Daily short volume (FINRA facilities)57.4% of 6,829,943 shares on October 2, 2026
5-day average short volume54.2%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Low risk

Filing-implied dilution signals for NAUT, detected from its recent SEC filings · based on capital-structure filings through 2026-09-18.

1 recent capital raiseATM program1 shelf registration

$125M ATM Program Established · $300M Universal Shelf Registered

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

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$2.23 +0.27% today
52-week range · as of 2026-09-11 $0.681 – $4.31
Market cap
$249.42M
Volume
14.2M (5.0× avg)
3-mo avg 2.9M
Live data · 2026-10-04 13:27 UTC · Market closed

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feed NAUT - Latest Insights

NAUT
Sep 11, 2026, 5:08 PM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
7
Price at Filing: $1.01
Real-time Price: $2.23 info
Change: +$1.22 (+121%) info
Market Cap: $249.42M info
NAUT
Aug 28, 2026, 7:43 PM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
7
Price at Filing: $0.890
Real-time Price: $2.23 info
Change: +$1.34 (+151%) info
Market Cap: $249.42M info
NAUT
Aug 14, 2026, 5:20 PM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
7
Price at Filing: $0.910
Real-time Price: $2.23 info
Change: +$1.32 (+145%) info
Market Cap: $249.42M info
NAUT
Jul 28, 2026, 4:06 PM EDT
Filing Type: 10-Q
Importance Score:
8
Price at Filing: $1.20
Real-time Price: $2.23 info
Change: +$1.03 (+86%) info
Market Cap: $249.42M info
NAUT
Jul 28, 2026, 8:10 AM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $1.51
Real-time Price: $2.23 info
Change: +$0.7205 (+48%) info
Market Cap: $249.42M info
NAUT
Jul 27, 2026, 7:29 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $1.72
Real-time Price: $2.23 info
Change: +$0.5105 (+30%) info
Market Cap: $249.42M info
NAUT
Jun 30, 2026, 5:13 PM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
8
Price at Filing: $1.87
Real-time Price: $2.23 info
Change: +$0.3605 (+19%) info
Market Cap: $249.42M info
NAUT
Jun 04, 2026, 4:54 PM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
8
Price at Filing: $2.68
Real-time Price: $2.23 info
Change: -$0.4495 (-17%) info
Market Cap: $249.42M info
NAUT
Apr 28, 2026, 4:07 PM EDT
Filing Type: 10-Q
Importance Score:
7
Price at Filing: $2.59
Real-time Price: $2.23 info
Change: -$0.3595 (-14%) info
Market Cap: $249.42M info
NAUT
Apr 27, 2026, 8:19 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $3.00
Real-time Price: $2.23 info
Change: -$0.7695 (-26%) info
Market Cap: $249.42M info
NAUT
Mar 18, 2026, 8:00 AM EDT
Source: GlobeNewswire
Importance Score:
8
Price at Filing: $2.67
Real-time Price: $2.23 info
Change: -$0.4413 (-17%) info
Market Cap: $249.42M info
NAUT
Mar 04, 2026, 7:33 PM EST
Filing Type: SCHEDULE 13D/A
Importance Score:
7
Price at Filing: $2.73
Real-time Price: $2.23 info
Change: -$0.4995 (-18%) info
Market Cap: $249.42M info
NAUT
Feb 26, 2026, 4:11 PM EST
Filing Type: 10-K
Importance Score:
7
Price at Filing: $2.42
Real-time Price: $2.23 info
Change: -$0.1895 (-8%) info
Market Cap: $249.42M info
NAUT
Feb 25, 2026, 6:46 PM EST
Filing Type: 8-K
Importance Score:
8
Price at Filing: $2.89
Real-time Price: $2.23 info
Change: -$0.6595 (-23%) info
Market Cap: $249.42M info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets