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IONS
NASDAQ Life Sciences

Olezarsen Shows Favorable Long-Term Safety, Hepatic Fat Trends Back to Baseline in 12-Month Data

Tom Rudovsky · Reported by Wiseek News
More coverage: Biotech Stocks · Healthcare
Sentiment info
Neutral
Importance info
8
Price
$73.24
Mkt Cap
$12.104B
52W Low
$34.775
52W High
$86.74
52W Position info
111% above low
Off High info
16% below high
Rel. Volume info
0.7× avg
Market data snapshot near publication time

IONS has more than doubled off its 52-week low of $34.775.

Summary

Ionis Pharmaceuticals reported 12-month MRI data for olezarsen, highlighting a favorable long-term safety profile and high patient retention. However, the data also showed mean hepatic fat fraction levels trending back toward baseline after 24 months of 80 mg treatment, with less pronounced reductions for patients who moved from 50 mg. This update follows an 8-K filed earlier today that characterized the long-term data as positive. The nuanced efficacy trend for hepatic fat, despite good safety, is a critical detail for investors to consider.

At the time of this announcement, IONS was trading at $73.24 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $12.1B. The 52-week trading range was $34.78 to $86.74. This news item was assessed with neutral market sentiment and an importance score of 8 out of 10. Source: Wiseek News.


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IONS - Latest Insights

IONS
Jul 09, 2026, 2:55 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $64.50
Real-time Price: $56.55 info
Change: -$7.95 (-12%) info
Market Cap: $9.346B info
IONS
Jul 09, 2026, 2:10 AM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $86.14
Real-time Price: $56.55 info
Change: -$29.59 (-34%) info
Market Cap: $9.346B info
IONS
Jun 30, 2026, 6:00 AM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $81.00
Real-time Price: $56.55 info
Change: -$24.45 (-30%) info
Market Cap: $9.346B info
IONS
Jun 26, 2026, 3:13 AM EDT
Source: Wiseek News
Importance Score:
7
Price at Filing: $78.60
Real-time Price: $56.55 info
Change: -$22.05 (-28%) info
Market Cap: $9.346B info
IONS
Jun 25, 2026, 3:01 AM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $78.00
Real-time Price: $56.55 info
Change: -$21.45 (-28%) info
Market Cap: $9.346B info