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IONS
NASDAQ Life Sciences

Ionis Q1 Revenue Soars 87%, Beats Estimates and Boosts Full-Year Guidance

Tom Rudovsky · Reported by Reuters
More coverage: Biotech Stocks · Healthcare
Sentiment info
Positive
Importance info
9
Price
$71.78
Mkt Cap
$11.851B
52W Low
$29.42
52W High
$86.74
52W Position info
144% above low
Off High info
17% below high
Rel. Volume info
1.1× avg
Market data snapshot near publication time

IONS has more than doubled off its 52-week low of $29.42.

Summary

Ionis Pharmaceuticals reported a strong first quarter, with revenue surging 87% year-over-year to $246 million, significantly exceeding analyst expectations of $195.63 million. This robust performance was primarily driven by higher product sales of TRYNGOLZA and DAWNZERA, as well as substantial R&D milestone payments totaling $95 million from partnerships. Following these results, the company raised its 2026 total revenue guidance to $875-900 million from the previous $800-825 million, and also increased annual olezarsen peak net sales guidance to over $3 billion for sHTG. While operating expenses rose due to commercialization investments, the strong revenue growth and improved outlook are highly positive for the stock, indicating strong execution and pipeline potential. Traders will monitor continued product sales growth and further pipeline advancements.

At the time of this announcement, IONS was trading at $71.78 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $11.9B. The 52-week trading range was $29.42 to $86.74. This news item was assessed with positive market sentiment and an importance score of 9 out of 10. Source: Reuters.


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IONS - Latest Insights

IONS
Jul 29, 2026, 7:31 AM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $56.49
Real-time Price: $55.03 info
Change: -$1.46 (-3%) info
Market Cap: $9.094B info
IONS
Jul 29, 2026, 7:00 AM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $56.09
Real-time Price: $55.03 info
Change: -$1.06 (-2%) info
Market Cap: $9.094B info
IONS
Jul 09, 2026, 2:55 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $64.50
Real-time Price: $55.03 info
Change: -$9.47 (-15%) info
Market Cap: $9.094B info
IONS
Jul 09, 2026, 2:10 AM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $86.14
Real-time Price: $55.03 info
Change: -$31.11 (-36%) info
Market Cap: $9.094B info
IONS
Jun 30, 2026, 6:00 AM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $81.00
Real-time Price: $55.03 info
Change: -$25.97 (-32%) info
Market Cap: $9.094B info