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Ensysce Biosciences, Inc.

corporate_fare Company Profile

Ensysce Biosciences, Inc.

ENSC·NASDAQ·Life Sciences·CIK 0001716947

Ensysce Biosciences, Inc. is a clinical stage pharmaceutical company focused on developing innovative solutions for severe pain relief. The company aims to reduce the potential for opioid misuse, abuse, and overdose. Ensysce Biosciences is currently developing product candidates designed to improve the safety of prescription drugs. Its primary focus is on opioid pain products and opioid use disorder products. The company was originally incorporated in Delaware in April 2003 as PharmacoFore, Inc., changing its name to Signature Therapeutics Inc. in January 2012. In December 2015, Signature merged with Ensysce Biosciences, Inc. ("Former Ensysce"). In June 2021, Former Ensysce merged with Leisure Acquisition Corporation, which then changed its name to Ensysce Biosciences, Inc. The principal executive office is located at 7946 Ivanhoe Avenue, Suite 201, La Jolla, California 92037.

Ensysce Biosciences, Inc. (NASDAQ:ENSC) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 25 items for ENSC at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-08-25, rated 8/10. Across its 20 most recent items scored 7 or higher, the top rating is 9/10, with 13 rated 8 or above. Recent SEC coverage for ENSC spans 8-K, SCHEDULE 13D/A, 4, 8-K/A.

Recent high-impact activity:

  • Nasdaq Extends Bid-Price Deadline to Feb 2027 but Flags Cy Merger as Change of Control
  • Ensysce Regains Nasdaq Equity Compliance, Seeks Second Bid-Price Grace Period
  • Chairman Bob Gower Discloses 6.1% Stake, Support Agreement for Cy Biopharma Merger
  • Director Bob Gower makes substantial open market purchase of ENSC shares
  • Ensysce Q2 Loss Widens to $2.6M, But $31M Cash Boost Extends Runway to 2027

Financial Snapshot

Fiscal year ended December 31, 2025
Revenue
$5.07M
Net Income
-$10.18M
Diluted EPS
-$3.98
Op. Cash Flow
-$7.81M
Free Cash Flow
-$7.93M
Operating Income
-$10.24M
Cash & Equivalents
$4.31M
Debt / Equity
0.00×
Net Margin
-200.8%
Shares Outstanding
4.57M sh
Source: 10-K · filed 2026-03-30 · accession 0001493152-26-013633

Short Interest & Short Volume

1.75 days to cover

FINRA reported short interest of 1,205,824 shares in ENSC as of the September 15, 2026 settlement, a 15.5% decrease from the prior period — about 1.8 days to cover at its recent average daily volume. On October 2, 2026, 26.4% of ENSC volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)1,205,824 shares as of September 15, 2026
Change vs prior period▼ 15.5%
Days to cover1.75 at avg daily volume of 690,453
Daily short volume (FINRA facilities)26.4% of 79,823 shares on October 2, 2026
5-day average short volume22.7%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Low risk

Filing-implied dilution signals for ENSC, detected from its recent SEC filings · based on capital-structure filings through 2026-05-15.

2 shelf registrations

Going Concern Warning Issued · Cash Balance Plummets

⚠ A more recent filing has been published for this ticker since this signal was computed; it may not yet be reflected — see the filings below.

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

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$0.3952 +0.00% today
52-week range · as of 2026-08-25 $0.23 – $2.75
Market cap
$7.69M
Volume
174K (0.3× avg)
3-mo avg 557.2K
Live data · 2026-10-05 03:00 UTC · Market closed

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feed ENSC - Latest Insights

ENSC
Aug 25, 2026, 5:12 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $0.3905
Real-time Price: $0.3952 info
Change: +$0.0047 (+1%) info
Market Cap: $7.685M info
ENSC
Aug 24, 2026, 5:13 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $0.3593
Real-time Price: $0.3952 info
Change: +$0.0359 (+10%) info
Market Cap: $7.685M info
ENSC
Aug 18, 2026, 12:30 PM EDT
Filing Type: SCHEDULE 13D/A
Importance Score:
7
Price at Filing: $0.370
Real-time Price: $0.3952 info
Change: +$0.0252 (+7%) info
Market Cap: $7.685M info
ENSC
Aug 18, 2026, 6:06 AM EDT
Filing Type: 4
Importance Score:
9
Price at Filing: $0.4154
Real-time Price: $0.3952 info
Change: -$0.0202 (-5%) info
Market Cap: $7.685M info
ENSC
Aug 13, 2026, 4:25 PM EDT
Source: Reuters
Importance Score:
7
Price at Filing: $0.3426
Real-time Price: $0.3952 info
Change: +$0.0526 (+15%) info
Market Cap: $7.685M info
ENSC
Aug 13, 2026, 4:20 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $0.343
Real-time Price: $0.3952 info
Change: +$0.0522 (+15%) info
Market Cap: $7.685M info
ENSC
Aug 06, 2026, 3:45 PM EDT
Filing Type: 8-K/A
Importance Score:
9
Price at Filing: $0.518
Real-time Price: $0.3952 info
Change: -$0.1228 (-24%) info
Market Cap: $7.685M info
ENSC
Aug 06, 2026, 8:20 AM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $0.72375
Real-time Price: $0.3952 info
Change: -$0.32855 (-45%) info
Market Cap: $7.685M info
ENSC
Jul 15, 2026, 4:15 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $0.2914
Real-time Price: $0.3952 info
Change: +$0.1038 (+36%) info
Market Cap: $7.685M info
ENSC
Jun 04, 2026, 4:42 PM EDT
Filing Type: S-3
Importance Score:
8
Price at Filing: $0.2999
Real-time Price: $0.3952 info
Change: +$0.0953 (+32%) info
Market Cap: $7.685M info
ENSC
May 22, 2026, 4:55 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $0.3013
Real-time Price: $0.3952 info
Change: +$0.0939 (+31%) info
Market Cap: $7.685M info
ENSC
May 15, 2026, 4:49 PM EDT
Source: Reuters
Importance Score:
9
Price at Filing: $0.275
Real-time Price: $0.3952 info
Change: +$0.1202 (+44%) info
Market Cap: $7.685M info
ENSC
May 15, 2026, 4:32 PM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $0.278
Real-time Price: $0.3952 info
Change: +$0.1172 (+42%) info
Market Cap: $7.685M info
ENSC
May 15, 2026, 4:20 PM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $0.275
Real-time Price: $0.3952 info
Change: +$0.1202 (+44%) info
Market Cap: $7.685M info
ENSC
May 15, 2026, 4:20 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $0.275
Real-time Price: $0.3952 info
Change: +$0.1202 (+44%) info
Market Cap: $7.685M info
ENSC
May 12, 2026, 8:00 AM EDT
Source: Access Newswire
Importance Score:
7
Price at Filing: $0.329
Real-time Price: $0.3952 info
Change: +$0.0662 (+20%) info
Market Cap: $7.685M info
ENSC
Apr 16, 2026, 8:00 AM EDT
Source: Access Newswire
Importance Score:
7
Price at Filing: $0.5351
Real-time Price: $0.3952 info
Change: -$0.1399 (-26%) info
Market Cap: $7.685M info
ENSC
Apr 08, 2026, 7:29 PM EDT
Filing Type: S-3
Importance Score:
9
Price at Filing: $0.4889
Real-time Price: $0.3952 info
Change: -$0.0937 (-19%) info
Market Cap: $7.685M info
ENSC
Apr 07, 2026, 9:05 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $0.5552
Real-time Price: $0.3952 info
Change: -$0.160 (-29%) info
Market Cap: $7.685M info
ENSC
Apr 07, 2026, 8:00 AM EDT
Source: Access Newswire
Importance Score:
8
Price at Filing: $0.5475
Real-time Price: $0.3952 info
Change: -$0.1523 (-28%) info
Market Cap: $7.685M info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets