COSCIENS Biopharma Inc.

COSCIENS is a life science company that develops and sells natural, plant-based active ingredients from oats and other renewable plant resources. The company uses proprietary manufacturing and extraction technologies. Its main business involves developing and selling natural products for the personal care, cosmetic, human, and animal health industries. COSCIENS' primary revenue comes from a commercial line of natural active ingredients, including beta glucan, avenanthramides (colloidal oat extract), oat powder, oat oil, and oat peptides. These ingredients are sold to the personal care, cosmetic, medical, and animal health industries through distribution partners and direct sales. A small part of current revenues comes from veterinary therapeutic products, such as an oat shampoo, an ear cleanser, and a dermal complex/conditioner. These products are manufactured and sold to veterinarians in Japan and other Asian countries. The company's main marketing strategy is to sell primarily through a distribution network rather than directly to end-users. Over the last decade, COSCIENS' development projects have focused on oats and creating new natural healthcare products or technologies. In November 2023, the company started a safety study for avenanthramides for potential use in managing inflammation-related conditions. The Phase 1-2a study assessed safety, tolerability, and pharmacokinetics. 72 healthy subjects completed the Phase 1 portion, with 48 in a single ascending dose (SAD) arm and 24 in a multiple ascending dose (MAD) arm.