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Caris Life Sciences, Inc.

corporate_fare Company Profile

Caris Life Sciences, Inc.

CAI·NASDAQ·Industrial Applications And Services·CIK 0002019410

Caris is an AI TechBio company and precision medicine pioneer that develops and commercializes solutions to transform healthcare using molecular information and artificial intelligence/machine learning algorithms. Founded in 2008, the company focuses on oncology and serves the clinical, academic, and biopharma markets. Caris's portfolio includes comprehensive, proprietary molecular profiling solutions and a multi-modal clinico-genomic dataset in oncology. As of December 31, 2025, Caris has performed sequencing on over 1,000,000 cases. The company's platform leverages next-generation sequencing ("NGS"), artificial intelligence ("AI") and machine learning ("ML") technologies, and high-performance computing. This platform enables the development of advanced precision medicine diagnostic solutions for the entire cancer care continuum, including early detection, minimal residual disease ("MRD") tracking, therapy selection, and treatment monitoring, as well as the creation of molecular signatures and the discovery and development of novel precision medicine therapeutics. Caris's Molecular Intelligence product portfolio, focused on oncology, includes: (1) the MI Profile Platform, which offers whole exome sequencing ("WES")/whole transcriptome sequencing ("WTS") tissue-based molecular profiling solutions, (2) the Caris Assure Platform, providing WES/WTS blood-based molecular profiling solutions, and (3) the Precision Whole Genome Platform, offering whole genome sequencing ("WGS") blood- and tissue-based profiling solutions.

Caris Life Sciences, Inc. (NASDAQ:CAI) is a publicly traded company in the Industrial Applications And Services sector. Wiseek has independently scored 13 items for CAI at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-09-04, rated 7/10. Across its 13 most recent items scored 7 or higher, the top rating is 9/10, with 11 rated 8 or above. Recent SEC coverage for CAI spans 4, 10-Q, 8-K, DEF 14A.

Recent high-impact activity:

  • President Spetzler Sells $14.8M in Stock to Cover Expiring Option Exercise
  • Caris Life Sciences Q2 Revenue Jumps 45% to $264M, Nears Breakeven
  • Caris Life Sciences Q2 Revenue Jumps 45%, Raises 2026 Guidance
  • Caris Life Sciences Initiates Share Repurchase Program
  • Caris Life Sciences Reports Robust Q1 2026 Results and Secures New $1.2 Billion Credit Facility

Financial Snapshot

Fiscal year ended December 31, 2025
Revenue
$812.03M
Net Income
-$68.09M
Diluted EPS
-$3.22
Op. Cash Flow
$83.16M
Free Cash Flow
$66.89M
Operating Income
$45.11M
Cash & Equivalents
$796.27M
Total Debt
$378.99M
Debt / Equity
0.66×
Net Margin
-8.4%
Shares Outstanding
282.53M sh
Source: 10-K · filed 2026-03-03 · accession 0002019410-26-000016

Short Interest & Short Volume

3.23 days to cover

FINRA reported short interest of 13,589,186 shares in CAI as of the October 15, 2026 settlement, a 2.2% decrease from the prior period — about 3.2 days to cover at its recent average daily volume. On November 2, 2026, 35.6% of CAI volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)13,589,186 shares as of October 15, 2026
Change vs prior period▼ 2.2%
Days to cover3.23 at avg daily volume of 4,208,854
Daily short volume (FINRA facilities)35.6% of 1,239,652 shares on November 2, 2026
5-day average short volume44.0%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

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$33.5 +4.36% today
52-week range · as of 2026-09-04 $14.19 – $36.65
Market cap
$9.47B
Volume
561.4K (0.2× avg)
3-mo avg 3.6M
Live data · 2026-11-03 16:21 UTC · Market open

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feed CAI - Latest Insights

CAI
Sep 04, 2026, 4:59 PM EDT
Filing Type: 4
Importance Score:
7
Price at Filing: $25.07
Real-time Price: $33.50 info
Change: +$8.43 (+34%) info
Market Cap: $9.467B info
CAI
Aug 05, 2026, 5:00 PM EDT
Filing Type: 10-Q
Importance Score:
8
Price at Filing: $19.11
Real-time Price: $33.50 info
Change: +$14.39 (+75%) info
Market Cap: $9.467B info
CAI
Aug 05, 2026, 4:59 PM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $18.70
Real-time Price: $33.50 info
Change: +$14.80 (+79%) info
Market Cap: $9.467B info
CAI
Jun 08, 2026, 8:30 AM EDT
Source: Dow Jones Newswires
Importance Score:
7
Price at Filing: $16.75
Real-time Price: $33.50 info
Change: +$16.75 (+100%) info
Market Cap: $9.467B info
CAI
May 08, 2026, 4:13 PM EDT
Filing Type: 10-Q
Importance Score:
8
Price at Filing: $16.19
Real-time Price: $33.50 info
Change: +$17.31 (+107%) info
Market Cap: $9.467B info
CAI
May 07, 2026, 4:37 PM EDT
Source: Wiseek News
Importance Score:
9
Price at Filing: $17.00
Real-time Price: $33.50 info
Change: +$16.50 (+97%) info
Market Cap: $9.467B info
CAI
May 07, 2026, 4:14 PM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $16.86
Real-time Price: $33.50 info
Change: +$16.64 (+99%) info
Market Cap: $9.467B info
CAI
May 04, 2026, 8:33 AM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $17.97
Real-time Price: $33.50 info
Change: +$15.53 (+86%) info
Market Cap: $9.467B info
CAI
Apr 23, 2026, 6:23 AM EDT
Filing Type: DEF 14A
Importance Score:
9
Price at Filing: $20.30
Real-time Price: $33.50 info
Change: +$13.20 (+65%) info
Market Cap: $9.467B info
CAI
Apr 02, 2026, 4:28 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $19.29
Real-time Price: $33.50 info
Change: +$14.21 (+74%) info
Market Cap: $9.467B info
CAI
Feb 27, 2026, 1:23 PM EST
Source: Dow Jones Newswires
Importance Score:
8
Price at Filing: $20.37
Real-time Price: $33.50 info
Change: +$13.14 (+64%) info
Market Cap: $9.467B info
CAI
Feb 26, 2026, 4:11 PM EST
Filing Type: 8-K
Importance Score:
9
Price at Filing: $22.48
Real-time Price: $33.50 info
Change: +$11.02 (+49%) info
Market Cap: $9.467B info
CAI
Jan 12, 2026, 9:00 AM EST
Filing Type: 8-K
Importance Score:
8
Price at Filing: $29.15
Real-time Price: $33.50 info
Change: +$4.35 (+15%) info
Market Cap: $9.467B info
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