Bionano Genomics, Inc.

Bionano Genomics, Inc. provides genome analysis solutions that help researchers and clinicians find answers in biology and medicine. The company aims to transform how the world views the genome using optical genome mapping ("OGM") solutions, nucleic acid extraction and purification systems, diagnostic services, and software. Bionano Genomics offers OGM solutions for basic, translational, and clinical research, as well as bioprocessing. Its platform-agnostic software integrates next-generation sequencing ("NGS"), microarray, and OGM data to analyze, visualize, interpret, and report copy number variants, single-nucleotide variants, and absence of heterozygosity across the genome in a single view. The company also provides nucleic acid extraction and purification solutions using its proprietary isotachophoresis ("ITP") technology. Through its Bionano Laboratories business, it offers OGM-based diagnostic testing services. The company develops, manufactures, markets, and sells OGM systems, including the Saphyr® system and the Stratys system. These systems provide OGM data for ultra-sensitive and ultra-specific detection of all classes of structural variation ("SV"). They are used to identify structural changes in chromosomes (cytogenetics) and to accelerate research in genetic disease, cancer, and cell and gene therapy applications. The systems consist of an instrument, chip consumables, reagents, and software with data analysis and visualization tools. OGM has demonstrated superior performance compared to current cytogenetic methods like karyotyping, fluorescence in-situ hybridization ("FISH"), Southern blot, and chromosomal microarray ("CMA") for SV detection, and can identify structural changes in chromosomes not detectable by current commercial gene sequencing solutions. Bionano Genomics also develops, manufactures, markets, and sells the Ionic® Purification system, which delivers high-quality DNA in a more natural, native form with fewer contaminants than other isolation and purification solutions.