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SYRE
NASDAQ Life Sciences

Spyre Therapeutics Completes Enrollment for SPY072 Phase 2 SKYWAY Trial, On Track for Q3/Q4 Data Readouts

Tom Rudovsky · Reported by GlobeNewswire
More coverage: Biotech Stocks · Healthcare
Sentiment info
Positive
Importance info
7
Price
$69.67
Mkt Cap
$6.006B
52W Low
$13.93
52W High
$78.8
52W Position info
400% above low
Off High info
12% below high
Rel. Volume info
0.7× avg
Market data snapshot near publication time

SYRE has more than doubled off its 52-week low of $13.93.

Summary

Spyre Therapeutics announced the completion of enrollment for all sub-studies in its Phase 2 SKYWAY basket trial evaluating SPY072 (anti-TL1A) for rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA). This operational milestone confirms the company is on track for its planned '6 in '26' Phase 2 readouts, following recent positive data for SPY001 and a significant public offering in April. Completing enrollment is a key de-risking step in clinical development, demonstrating pipeline execution. Topline data for RA is expected in Q3 2026, with PsA and axSpA readouts anticipated in Q4 2026.

At the time of this announcement, SYRE was trading at $69.67 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $6B. The 52-week trading range was $13.93 to $78.80. This news item was assessed with positive market sentiment and an importance score of 7 out of 10. Source: GlobeNewswire.


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8
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Filing Type: 4
Importance Score:
8
Price at Filing: $86.50
Real-time Price: $99.63 info
Change: +$13.13 (+15%) info
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Filing Type: SCHEDULE 13D/A
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9
Price at Filing: $86.50
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Market Cap: $8.704B info
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Jun 15, 2026, 8:03 AM EDT
Source: Wiseek News
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9
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Market Cap: $8.704B info
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Jun 15, 2026, 8:01 AM EDT
Filing Type: 8-K
Importance Score:
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Price at Filing: $82.50
Real-time Price: $99.63 info
Change: +$17.13 (+21%) info
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Jun 03, 2026, 8:00 AM EDT
Source: GlobeNewswire
Importance Score:
7
Price at Filing: $69.67
Real-time Price: $99.63 info
Change: +$29.96 (+43%) info
Market Cap: $8.704B info
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Filing Type: 8-K
Importance Score:
7
Price at Filing: $70.54
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Change: +$29.09 (+41%) info
Market Cap: $8.704B info
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May 05, 2026, 8:00 AM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $68.13
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Market Cap: $8.704B info