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ONC
NASDAQ Life Sciences

CEO Oyler Files to Sell $156M in BeOne Medicines Stock, Upsizing Prior Plan

Arie Shkolnikov · Analysis by Wiseek AI
More coverage: Biotech Stocks · Healthcare
Sentiment info
Negative
Importance info
8
Price
$306.56
Mkt Cap
$35.595B
52W Low
$249.12
52W High
$385.22
52W Position info
23% above low
Off High info
20% below high
Rel. Volume info
1.6× avg
Market data snapshot near publication time

ONC sits 23% above its 52-week low of $249.12.

Summary

BeOne Medicines CEO John V. Oyler filed to sell $156.1 million in stock, sharply upsizing a prior $45.4 million plan filed days ago, adding to $37 million in recent sales.


Key Events · Ownership and Investor Activity · ONC

  • CEO Proposes $156M Stock Sale

    John V. Oyler filed a Form 144 to sell 513,574 ADSs worth approximately $156.1 million, a significant increase from the $45.4 million sale filed on July 10, 2026.

  • Source of Shares: Options and RSUs

    The shares to be sold include 425,590 from option exercises over the next three months, 75,723 from previously exercised options, and 12,261 from RSU vesting.

  • Recent Sales Add to Overhang

    In the past three months, Oyler and his foundation sold 123,751 shares for $37 million under 10b5-1 plans, indicating ongoing liquidity needs.

  • 10b5-1 Plan Adopted March 2026

    The sales are executed under a pre-arranged trading plan adopted on March 10, 2026, providing a defense against insider trading allegations but not eliminating negative signaling.


Analysis · ONC · Life Sciences

CEO John V. Oyler filed a new Form 144 to sell 513,574 ADSs worth approximately $156.1 million, a dramatic increase from the $45.4 million sale filed just four days ago. The shares come from option exercises and RSU vesting, and the filing is part of a 10b5-1 plan adopted in March 2026. Combined with recent sales by Oyler and his foundation totaling $37 million over the past three months, the total planned and executed sales represent a significant liquidity event by the CEO. While pre-planned sales under 10b5-1 are routine, the sheer size and rapid escalation raise questions about insider sentiment, especially following strong Q1 results and a major FDA approval.

How filings like this one have moved

In the 30 days to Sep 11, 2026, 35.7% of the 1694 measured filings Wiseek scored 8 moved their stock by 5% or more by the next session's close. The median move was -0.10%. These are measured outcomes after filings of this importance, not a forecast for this one.

Measured one observation per ticker per day, after exclusions. Current figures: Filing Impact Tracker · open dataset

At the time of this filing, ONC was trading at $306.56 on NASDAQ in the Life Sciences sector, with a market capitalization of approximately $35.6B. The 52-week trading range was $249.12 to $385.22. This filing was assessed with negative market sentiment and an importance score of 8 out of 10.

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ONC - Latest Insights

ONC
Sep 08, 2026, 4:26 PM EDT
Filing Type: 144
Importance Score:
7
Price at Filing: $348.48
Real-time Price: $346.51 info
Change: -$1.97 (-0.57%) info
Market Cap: $39.037B info
ONC
Aug 05, 2026, 6:04 AM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $335.49
Real-time Price: $346.51 info
Change: +$11.02 (+3%) info
Market Cap: $39.037B info
ONC
Aug 05, 2026, 6:02 AM EDT
Filing Type: 8-K
Importance Score:
9
Price at Filing: $335.49
Real-time Price: $346.51 info
Change: +$11.02 (+3%) info
Market Cap: $39.037B info
ONC
Aug 05, 2026, 6:00 AM EDT
Source: Dow Jones Newswires
Importance Score:
9
Price at Filing: $329.01
Real-time Price: $346.51 info
Change: +$17.50 (+5%) info
Market Cap: $39.037B info
ONC
Jul 10, 2026, 4:36 PM EDT
Filing Type: 144
Importance Score:
8
Price at Filing: $298.70
Real-time Price: $346.51 info
Change: +$47.81 (+16%) info
Market Cap: $39.037B info