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PFE
NYSE Life Sciences

Pfizer's Late-Stage Lung Cancer Drug Trial Misses Primary Endpoint

Tom Rudovsky · Reported by Dow Jones Newswires
More coverage: Pharmaceutical Stocks · Healthcare
Sentiment info
Negative
Importance info
8
Price
$24.65
Mkt Cap
$142.942B
52W Low
$23.11
52W High
$28.745
52W Position info
6.7% above low
Off High info
14% below high
Rel. Volume info
1.1× avg
Market data snapshot near publication time

PFE is trading near its 52-week low of $23.11 (6.7% above the low).

Summary

Pfizer's Phase 3 trial for its lung cancer drug, sigvotatug vedotin, failed to meet its primary endpoint of statistically significant improvement in overall survival for non-squamous non-small cell lung cancer. This is a setback for the company's oncology pipeline, contrasting with recent positive news regarding other drug trials and strong financial performance. While the drug showed strong efficacy in a subset of patients and a manageable safety profile, this specific indication is now in question. Pfizer continues to test the drug in a separate first-line treatment trial.

At the time of this announcement, PFE was trading at $24.65 on NYSE in the Life Sciences sector, with a market capitalization of approximately $142.9B. The 52-week trading range was $23.11 to $28.75. This news item was assessed with negative market sentiment and an importance score of 8 out of 10. Source: Dow Jones Newswires.


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PFE - Latest Insights

PFE
Aug 04, 2026, 12:49 PM EDT
Source: Benzinga
Importance Score:
9
Price at Filing: $25.45
Real-time Price: $25.85 info
Change: +$0.405 (+2%) info
Market Cap: $147.337B info
PFE
Aug 04, 2026, 10:30 AM EDT
Source: Reuters
Importance Score:
8
Price at Filing: $24.89
Real-time Price: $25.85 info
Change: +$0.965 (+4%) info
Market Cap: $147.337B info
PFE
Aug 04, 2026, 7:12 AM EDT
Source: Dow Jones Newswires
Importance Score:
8
Price at Filing: $25.07
Real-time Price: $25.85 info
Change: +$0.7802 (+3%) info
Market Cap: $147.337B info
PFE
Aug 04, 2026, 7:04 AM EDT
Filing Type: 10-Q
Importance Score:
9
Price at Filing: $25.11
Real-time Price: $25.85 info
Change: +$0.7395 (+3%) info
Market Cap: $147.337B info
PFE
Aug 04, 2026, 7:02 AM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $24.94
Real-time Price: $25.85 info
Change: +$0.910 (+4%) info
Market Cap: $147.337B info