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PFE
NYSE Life Sciences

Pfizer's Late-Stage Lung Cancer Drug Trial Misses Primary Endpoint

Tom Rudovsky · Reported by Dow Jones Newswires
More coverage: Pharmaceutical Stocks · Healthcare
Sentiment info
Negative
Importance info
8
Price
$24.65
Mkt Cap
$142.942B
52W Low
$23.11
52W High
$28.745
52W Position info
6.7% above low
Off High info
14% below high
Rel. Volume info
1.1× avg
Market data snapshot near publication time

PFE is trading near its 52-week low of $23.11 (6.7% above the low).

Summary

Pfizer's Phase 3 trial for its lung cancer drug, sigvotatug vedotin, failed to meet its primary endpoint of statistically significant improvement in overall survival for non-squamous non-small cell lung cancer. This is a setback for the company's oncology pipeline, contrasting with recent positive news regarding other drug trials and strong financial performance. While the drug showed strong efficacy in a subset of patients and a manageable safety profile, this specific indication is now in question. Pfizer continues to test the drug in a separate first-line treatment trial.

At the time of this announcement, PFE was trading at $24.65 on NYSE in the Life Sciences sector, with a market capitalization of approximately $142.9B. The 52-week trading range was $23.11 to $28.75. This news item was assessed with negative market sentiment and an importance score of 8 out of 10. Source: Dow Jones Newswires.


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PFE - Latest Insights

PFE
Oct 01, 2026, 3:00 AM EDT
Source: Wiseek News
Importance Score:
8
Price at Filing: $28.59
Real-time Price: $28.40 info
Change: -$0.190 (-0.66%) info
Market Cap: $162.555B info
PFE
Oct 01, 2026, 2:30 AM EDT
Source: BusinessWire
Importance Score:
8
Price at Filing: $28.59
Real-time Price: $28.40 info
Change: -$0.190 (-0.66%) info
Market Cap: $162.555B info
PFE
Sep 21, 2026, 2:15 AM EDT
Source: Seeking Alpha
Importance Score:
7
Price at Filing: $27.62
Real-time Price: $28.40 info
Change: +$0.780 (+3%) info
Market Cap: $162.555B info
PFE
Sep 07, 2026, 2:46 AM EDT
Source: CNBC TV18
Importance Score:
7
Price at Filing: $28.44
Real-time Price: $28.40 info
Change: -$0.040 (-0.14%) info
Market Cap: $162.555B info
PFE
Aug 27, 2026, 4:30 PM EDT
Source: BusinessWire
Importance Score:
7
Price at Filing: $28.05
Real-time Price: $28.41 info
Change: +$0.360 (+1%) info
Market Cap: $162.555B info