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Alto Neuroscience, Inc.

corporate_fare Company Profile

Alto Neuroscience, Inc.

ANRO·NYSE·Life Sciences·CIK 0001999480

Alto is a clinical-stage biopharmaceutical company focused on developing personalized treatments for psychiatric conditions. The company utilizes its proprietary Precision Psychiatry Platform to identify brain-based biomarkers, aiming to predict which patients will respond to its product candidates. Alto's pipeline includes seven clinical-stage assets targeting major depressive disorder (MDD), bipolar depression (BPD), treatment resistant depression (TRD), schizophrenia, and Parkinson's disease. Its most advanced program is ALTO-207. Founded in 2019, Alto seeks to innovate psychiatry by moving away from a broad approach to central nervous system (CNS) drug development. The company believes its precision approach, which uses neurobiological insights, can lead to more effective treatments for specific patient populations. Alto estimates its portfolio has the potential to impact over 25 million patients in the United States. The Platform uses modern neurobiology measurement tools and data science analytics.

Alto Neuroscience, Inc. (NYSE:ANRO) is a publicly traded company in the Life Sciences sector. Wiseek has independently scored 17 items for ANRO at importance 7 or higher on its 1–10 market-impact scale. Its most recent item scored 7 or higher is dated 2026-08-12, rated 7/10. Across its 17 most recent items scored 7 or higher, the top rating is 9/10, with 9 rated 8 or above. Recent SEC coverage for ANRO spans 10-Q, 8-K, 424B5, DEF 14A.

Recent high-impact activity:

  • Alto Neuroscience Q2 2026: $27.6M Net Loss, CFO Adopts 10b5-1 Plan
  • Alto Neuroscience Expands ALTO-207 Program with New Phase 3 Trial Amid Q2 Loss
  • $94M Stock Offering at 7% Discount to Fund Key Drug Trial
  • Alto Neuroscience prices a $100M public offering at $26.48 per share to fund Phase 3 trials of ALTO-207
  • Alto Neuroscience Raises $100M in Public Offering to Fund Phase 3 Trial and Extend Cash Runway

Financial Snapshot

Fiscal year ended December 31, 2025
Net Income
-$63.24M
Diluted EPS
-$2.19
Op. Cash Flow
-$51.77M
Free Cash Flow
-$51.79M
Operating Income
-$66.36M
Cash & Equivalents
$176.48M
Total Debt
$16.76M
Debt / Equity
0.11×
Shares Outstanding
31.92M sh
Source: 10-K · filed 2026-03-16 · accession 0001999480-26-000002

Short Interest & Short Volume

9.08 days to cover

FINRA reported short interest of 4,174,082 shares in ANRO as of the September 15, 2026 settlement, a 8.8% increase from the prior period — about 9.1 days to cover at its recent average daily volume. On October 2, 2026, 79.3% of ANRO volume reported to FINRA trade-reporting facilities was marked short.

Short interest (bi-monthly positions)4,174,082 shares as of September 15, 2026
Change vs prior period▲ 8.8%
Days to cover9.08 at avg daily volume of 459,493
Daily short volume (FINRA facilities)79.3% of 204,124 shares on October 2, 2026
5-day average short volume64.2%

Daily short sale volume covers trades reported to FINRA trade-reporting facilities and is not the same as short interest (bi-monthly reported positions). Source: FINRA — FINRA is the owner and source of this short interest and short sale volume data; it may not be redistributed.

Dilution Risk

Low risk

Filing-implied dilution signals for ANRO, detected from its recent SEC filings · based on capital-structure filings through 2026-07-14.

1 recent capital raise1 shelf registration

Public Offering Completed · Strategic Use of Proceeds

⚠ A more recent filing has been published for this ticker since this signal was computed; it may not yet be reflected — see the filings below.

A filing-implied signal, not a realized share count. How Wiseek tracks dilution →

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$24.8
52-week range · as of 2026-08-12 $3.02 – $29.7
Market cap
$973.2M
Volume
660.7K (1.2× avg)
3-mo avg 567.3K
Live data · 2026-10-05 02:49 UTC · Market closed

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feed ANRO - Latest Insights

ANRO
Aug 12, 2026, 4:27 PM EDT
Filing Type: 10-Q
Importance Score:
7
Price at Filing: $28.50
Real-time Price: $24.80 info
Change: -$3.70 (-13%) info
Market Cap: $973.204M info
ANRO
Aug 12, 2026, 4:14 PM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $29.18
Real-time Price: $24.80 info
Change: -$4.38 (-15%) info
Market Cap: $973.204M info
ANRO
Jul 14, 2026, 6:13 AM EDT
Source: Wiseek News
Importance Score:
8
Price at Filing: $28.50
Real-time Price: $24.80 info
Change: -$3.70 (-13%) info
Market Cap: $973.204M info
ANRO
Jul 14, 2026, 6:04 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $28.50
Real-time Price: $24.80 info
Change: -$3.70 (-13%) info
Market Cap: $973.204M info
ANRO
Jul 14, 2026, 6:03 AM EDT
Filing Type: 424B5
Importance Score:
8
Price at Filing: $28.50
Real-time Price: $24.80 info
Change: -$3.70 (-13%) info
Market Cap: $973.204M info
ANRO
Jul 13, 2026, 7:39 AM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $26.48
Real-time Price: $24.80 info
Change: -$1.68 (-6%) info
Market Cap: $973.204M info
ANRO
May 28, 2026, 8:18 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $20.44
Real-time Price: $24.80 info
Change: +$4.36 (+21%) info
Market Cap: $973.204M info
ANRO
May 13, 2026, 4:21 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $22.85
Real-time Price: $24.80 info
Change: +$1.95 (+9%) info
Market Cap: $973.204M info
ANRO
May 13, 2026, 7:30 AM EDT
Filing Type: 10-Q
Importance Score:
7
Price at Filing: $24.39
Real-time Price: $24.80 info
Change: +$0.410 (+2%) info
Market Cap: $973.204M info
ANRO
May 13, 2026, 7:04 AM EDT
Filing Type: 8-K
Importance Score:
7
Price at Filing: $24.39
Real-time Price: $24.80 info
Change: +$0.410 (+2%) info
Market Cap: $973.204M info
ANRO
Apr 01, 2026, 5:02 PM EDT
Source: Dow Jones Newswires
Importance Score:
9
Price at Filing: $22.75
Real-time Price: $24.80 info
Change: +$2.05 (+9%) info
Market Cap: $973.204M info
ANRO
Apr 01, 2026, 4:55 PM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $22.00
Real-time Price: $24.80 info
Change: +$2.80 (+13%) info
Market Cap: $973.204M info
ANRO
Mar 26, 2026, 4:06 PM EDT
Filing Type: DEF 14A
Importance Score:
7
Price at Filing: $20.82
Real-time Price: $24.80 info
Change: +$3.98 (+19%) info
Market Cap: $973.204M info
ANRO
Mar 16, 2026, 12:17 PM EDT
Source: Dow Jones Newswires
Importance Score:
8
Price at Filing: $24.62
Real-time Price: $24.80 info
Change: +$0.1801 (+0.73%) info
Market Cap: $973.204M info
ANRO
Mar 16, 2026, 7:08 AM EDT
Filing Type: 8-K
Importance Score:
8
Price at Filing: $23.40
Real-time Price: $24.80 info
Change: +$1.40 (+6%) info
Market Cap: $973.204M info
ANRO
Mar 16, 2026, 6:07 AM EDT
Filing Type: 10-K
Importance Score:
7
Price at Filing: $22.36
Real-time Price: $24.80 info
Change: +$2.44 (+11%) info
Market Cap: $973.204M info
ANRO
Mar 16, 2026, 6:04 AM EDT
Source: Dow Jones Newswires
Importance Score:
7
Price at Filing: $22.36
Real-time Price: $24.80 info
Change: +$2.44 (+11%) info
Market Cap: $973.204M info
Research tools: Filing Impact Index Dilution Tracker Split Calendar Open Datasets