Absci Details Significant Clinical Progress for Lead Asset ABS-201 at J.P. Morgan Conference

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This 8-K filing, incorporating the J.P. Morgan Healthcare Conference presentation, provides a highly positive and detailed update on Absci's clinical pipeline and financial health. The initiation of two Phase 1/2a trials for ABS-201 in significant indications like androgenetic alopecia and endometriosis, coupled with clear timelines for upcoming clinical readouts, de-risks the development path and offers multiple near-term catalysts for investors. The reported cash runway into 1H 2028 further strengthens the company's position, providing stability to execute on its clinical programs. The presentation reinforces the potential of Absci's AI-driven drug creation platform to address large unmet medical needs.

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• Clinical Trial Initiation

  Absci initiated Phase 1/2a trials for its lead asset ABS-201 in both androgenetic alopecia (AGA) and endometriosis in December 2025.

• Upcoming Catalysts for AGA

  The company expects PK and interim safety data for ABS-201 in AGA in 1H 2026, followed by a 13-week interim Proof-of-Concept (PoC) readout in 2H 2026, and topline 26-week PoC data in early 2027.

• Endometriosis Development

  Absci anticipates initiating a Phase 2 trial for ABS-201 in endometriosis in 2H 2026.

• Financial Runway

  The company reported over $143 million in cash, cash equivalents, and marketable securities as of December 31, 2025, providing a runway into the first half of 2028.

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This 8-K filing, incorporating the J.P. Morgan Healthcare Conference presentation, provides a highly positive and detailed update on Absci's clinical pipeline and financial health. The initiation of two Phase 1/2a trials for ABS-201 in significant indications like androgenetic alopecia and endometriosis, coupled with clear timelines for upcoming clinical readouts, de-risks the development path and offers multiple near-term catalysts for investors. The reported cash runway into 1H 2028 further strengthens the company's position, providing stability to execute on its clinical programs. The presentation reinforces the potential of Absci's AI-driven drug creation platform to address large unmet medical needs.